Publications

2021

 Lemoine MD, S., Salerno, F. R., Akbari, A., & McIntyre Md, C. W. (2021). Influence of Dialysate Sodium Prescription on Skin and Muscle Sodium Concentration. American journal of kidney diseases: the official journal of the National Kidney Foundation, S0272-6386(21)00005-6. Advance online publication. https://doi.org/10.1053/j.ajkd.2020.11.025

2020

Hur, L., & McIntyre, C. W. (2020). Current and novel imaging techniques to evaluate myocardial dysfunction during hemodialysis. Current opinion in nephrology and hypertension, 29(6), 555–563. https://doi.org/10.1097/MNH.0000000000000645

Chen, J., Martin, C., Ball, I. M., McIntyre, C. W., & Slessarev, M. (2020). Impact of Graded Passive Cycling on Hemodynamics, Cerebral Blood Flow, and Cardiac Function in Septic ICU Patients. Frontiers in medicine, 7, 569679. https://doi.org/10.3389/fmed.2020.569679

Penny, J. D., Salerno, F. R., Akbari, A., & McIntyre, C. W. (2020). Pruritus: Is there a grain of salty truth? Hemodialysis international. International Symposium on Home Hemodialysis, 10.1111/hdi.12885. Advance online publication. https://doi.org/10.1111/hdi.12885

Jefferies, H. J., Lemoine, S., & McIntyre, C. W. (2020). High magnesium dialysate does not improve intradialytic hemodynamics or abrogate myocardial stunning. Hemodialysis international. International Symposium on Home Hemodialysis, 24(4), 506–515. https://doi.org/10.1111/hdi.12863

Fraser, S. D., Barker, J., Roderick, P. J., Yuen, H. M., Shardlow, A., Morris, J. E., McIntyre, N. J., Fluck, R. J., McIntyre, C. W., & Taal, M. W. (2020). Health-related quality of life, functional impairment and comorbidity in people with mild-to-moderate chronic kidney disease: a cross-sectional study. BMJ open, 10(8), e040286. https://doi.org/10.1136/bmjopen-2020-040286

Honarmand, K., Lalli, R. S., Priestap, F., Chen, J. L., McIntyre, C. W., Owen, A. M., & Slessarev, M. (2020). Natural History of Cognitive Impairment in Critical Illness Survivors. A Systematic Review. American journal of respiratory and critical care medicine, 202(2), 193–201. https://doi.org/10.1164/rccm.201904-0816CI

Shardlow, A., McIntyre, N. J., Kolhe, N. V., Nellums, L. B., Fluck, R. J., McIntyre, C. W., & Taal, M. W. (2020). The association of skin autofluorescence with cardiovascular events and all-cause mortality in persons with chronic kidney disease stage 3: A prospective cohort study. PLoS medicine, 17(7), e1003163. https://doi.org/10.1371/journal.pmed.1003163

Kharche, S. R., Desai, K., & McIntyre, C. W. (2020). Elucidating the relationship between arrhythmia and ischemic heterogeneity: an in-silico study. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2020, 2434–2437. https://doi.org/10.1109/EMBC44109.2020.9176737

Joseph, J. J., McIntyre, C. W., & Kharche, S. R. (2020). Proarrhythmic Effects of Electrolyte Imbalance in Virtual Human Atrial and Ventricular Cardiomyocytes. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2020, 2315–2318. https://doi.org/10.1109/EMBC44109.2020.9176060

Millar, S. A., John, S. G., McIntyre, C. W., Ralevic, V., Anderson, S. I., & O'Sullivan, S. E. (2020). An Investigation Into the Role of Osteocalcin in Human Arterial Smooth Muscle Cell Calcification. Frontiers in endocrinology, 11, 369. https://doi.org/10.3389/fendo.2020.00369

Qirjazi, E., Salerno, F. R., Akbari, A., Hur, L., Penny, J., Scholl, T., & McIntyre, C. W. (2020). Tissue sodium concentrations in chronic kidney disease and dialysis patients by lower leg sodium-23 magnetic resonance imaging. Nephrology, dialysis, transplantation: official publication of the European Dialysis and Transplant Association - European Renal Association, gfaa036. Advance online publication. https://doi.org/10.1093/ndt/gfaa036

Flythe, J. E., Chang, T. I., Gallagher, M. P., Lindley, E., Madero, M., Sarafidis, P. A., Unruh, M. L., Wang, A. Y., Weiner, D. E., Cheung, M., Jadoul, M., Winkelmayer, W. C., Polkinghorne, K. R., & Conference Participants (2020). Blood pressure and volume management in dialysis: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney international, 97(5), 861–876. https://doi.org/10.1016/j.kint.2020.01.046

Al-Jaishi, A. A., McIntyre, C. W., Sontrop, J. M., Dixon, S. N., Anderson, S., Bagga, A., Benjamin, D., Berry, D., Blake, P. G., Chambers, L., Chan, P., Delbrouck, N., Devereaux, P. J., Ferreira-Divino, L. F., Goluch, R., Gregor, L., Grimshaw, J. M., Hanson, G., Iliescu, E., Jain, A. K., … Garg, A. X. (2020). Major Outcomes with Personalized Dialysate TEMPerature (MyTEMP): Rationale and Design of a Pragmatic, Registry-Based, Cluster Randomized Controlled Trial. Canadian journal of kidney health and disease, 7, 2054358119887988. https://doi.org/10.1177/2054358119887988

Marinovich, R., Li, Z., Tamasi, T., Quinn, K., Wong, S., & McIntyre, C. W. (2020). Hemodynamic response to non-pneumatic anti-shock compression garments in patients with renal dysfunction. BMC nephrology, 21(1), 15. https://doi.org/10.1186/s12882-019-1680-8

2019

Lee, E. J., Patel, A., Acedillo, R. R., Bachynski, J. C., Barrett, I., Basile, E., Battistella, M., Benjamin, D., Berry, D., Blake, P. G., Chan, P., Bohm, C. J., Clemens, K. K., Cook, C., Dember, L., Dirk, J. S., Dixon, S., Fowler, E., Getchell, L., Gholami, N., … Garg, A. X. (2019). Cultivating Innovative Pragmatic Cluster-Randomized Registry Trials Embedded in Hemodialysis Care: Workshop Proceedings From 2018. Canadian journal of kidney health and disease, 6, 2054358119894394. https://doi.org/10.1177/2054358119894394

Altamirano-Diaz, L., Kassay, A. D., Serajelahi, B., McIntyre, C. W., Filler, G., & Kharche, S. R. (2019). Arterial Hypertension and Unusual Ascending Aortic Dilatation in a Neonate with Acute Kidney Injury: Mechanistic Computer Modeling. Frontiers in physiology, 10, 1391. https://doi.org/10.3389/fphys.2019.01391

Penny, J. D., Salerno, F. R., Brar, R., Garcia, E., Rossum, K., McIntyre, C. W., & Bohm, C. J. (2019). Intradialytic exercise preconditioning: an exploratory study on the effect on myocardial stunning. Nephrology, dialysis, transplantation: official publication of the European Dialysis and Transplant Association - European Renal Association, 34(11), 1917–1923. https://doi.org/10.1093/ndt/gfy376

McIntyre, N. J., Shardlow, A., Fluck, R. J., McIntyre, C. W., & Taal, M. W. (2019). Determinants of change in arterial stiffness over 5 years in early chronic kidney disease. Nephrology, dialysis, transplantation: official publication of the European Dialysis and Transplant Association - European Renal Association, gfz170. Advance online publication. https://doi.org/10.1093/ndt/gfz170

Salerno, F. R., Crowley, L. E., Odudu, A., & McIntyre, C. W. (2019). Remote Ischemic Preconditioning Protects Against Hemodialysis-Induced Cardiac Injury. Kidney international reports, 5(1), 99–103. https://doi.org/10.1016/j.ekir.2019.08.016

Chen, J., Martin, C., McIntyre, C. W., Ball, I. M., Duffin, J., & Slessarev, M. (2019). Impact of Graded Passive Cycling on Hemodynamics, Brain, and Heart Perfusion in Healthy Adults. Frontiers in medicine, 6, 186. https://doi.org/10.3389/fmed.2019.00186

Slessarev, M., Salerno, F., Ball, I. M., & McIntyre, C. W. (2019). Continuous renal replacement therapy is associated with acute cardiac stunning in critically ill patients. Hemodialysis international. International Symposium on Home Hemodialysis, 23(3), 325–332. https://doi.org/10.1111/hdi.12760

Marants, R., Qirjazi, E., Grant, C. J., Lee, T. Y., & McIntyre, C. W. (2019). Renal Perfusion during Hemodialysis: Intradialytic Blood Flow Decline and Effects of Dialysate Cooling. Journal of the American Society of Nephrology: JASN, 30(6), 1086–1095. https://doi.org/10.1681/ASN.2018121194

House, A. A., Wanner, C., Sarnak, M. J., Piña, I. L., McIntyre, C. W., Komenda, P., Kasiske, B. L., Deswal, A., deFilippi, C. R., Cleland, J., Anker, S. D., Herzog, C. A., Cheung, M., Wheeler, D. C., Winkelmayer, W. C., McCullough, P. A., & Conference Participants (2019). Heart failure in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney international, 95(6), 1304–1317. https://doi.org/10.1016/j.kint.2019.02.022

Moist, L. M., & McIntyre, C. W. (2019). Cerebral Ischemia and Cognitive Dysfunction in Patients on Dialysis. Clinical journal of the American Society of Nephrology: CJASN, 14(6), 914–916. https://doi.org/10.2215/CJN.00400119

Honarmand, K., Malik, S., Wild, C., Gonzalez-Lara, L. E., McIntyre, C. W., Owen, A. M., & Slessarev, M. (2019). Feasibility of a web-based neurocognitive battery for assessing cognitive function in critical illness survivors. PloS one, 14(4), e0215203. https://doi.org/10.1371/journal.pone.0215203

Grant, C. J., Huang, S. S., & McIntyre, C. W. (2019). Hepato-splanchnic circulatory stress: An important effect of hemodialysis. Seminars in dialysis, 32(3), 237–242. https://doi.org/10.1111/sdi.12782

Eldehni, M. T., Odudu, A., & Mcintyre, C. W. (2019). Brain white matter microstructure in end-stage kidney disease, cognitive impairment, and circulatory stress. Hemodialysis international. International Symposium on Home Hemodialysis, 23(3), 356–365. https://doi.org/10.1111/hdi.12754

MacLaughlin, H. L., Blacklock, R. M., Wright, K., Pot, G., Jayawardene, S., McIntyre, C. W., Macdougall, I. C., & Selby, N. M. (2019). Obesity and recovery from acute kidney injury (Ob AKI): a prospective cohort feasibility study. BMJ open, 9(3), e024033. https://doi.org/10.1136/bmjopen-2018-024033

2018

Grant, C. J., Wade, T. P., McKenzie, C. A., Filler, G., McIntyre, C. W., & Huang, S. S. (2018). Effect of ultrafiltration during hemodialysis on hepatic and total-body water: an observational study. BMC nephrology, 19(1), 356. https://doi.org/10.1186/s12882-018-1150-8

Gomes, J., Lucien, F., Cooper, T. T., Kim, Y., Williams, K. C., Liao, X., Kaufman, L., Lagugné-Labarthet, F., Kenyon, O., Boysen, J., Kay, N. E., McIntyre, C. W., & Leong, H. S. (2018). Analytical Considerations in Nanoscale Flow Cytometry of Extracellular Vesicles to Achieve Data Linearity. Thrombosis and haemostasis, 118(9), 1612–1624. https://doi.org/10.1055/s-0038-1668544

Filler, G., & McIntyre, C. W. (2018). More Realistic Estimation of Time to ESRD in Children. American journal of kidney diseases: the official journal of the National Kidney Foundation, 71(6), 766–768. https://doi.org/10.1053/j.ajkd.2018.02.356

Kharche, S. R., So, A., Salerno, F., Lee, T. Y., Ellis, C., Goldman, D., & McIntyre, C. W. (2018). Computational Assessment of Blood Flow Heterogeneity in Peritoneal Dialysis Patients' Cardiac Ventricles. Frontiers in physiology, 9, 511. https://doi.org/10.3389/fphys.2018.00511

Szeto, C. C., McIntyre, C. W., & Li, P. K. (2018). Circulating Bacterial Fragments as Cardiovascular Risk Factors in CKD. Journal of the American Society of Nephrology: JASN, 29(6), 1601–1608. https://doi.org/10.1681/ASN.2018010068

Derynck, M. R., Jones, S., Rachinsky, I. V., McIntyre, C. W., Blake, P., & Filler, G. (2018). Successful Reintroduction of Peritoneal Dialysis After Peritoneal-Pericardial Fistula in a Child: A Case Report. Peritoneal dialysis international: journal of the International Society for Peritoneal Dialysis, 38(2), 154–156. https://doi.org/10.3747/pdi.2017.00049

McIntyre, C. W., & Salerno, F. R. (2018). Diagnosis and Treatment of Intradialytic Hypotension in Maintenance Hemodialysis Patients. Clinical journal of the American Society of Nephrology: CJASN, 13(3), 486–489. https://doi.org/10.2215/CJN.11131017

Penny, J. D., Grant, C., Salerno, F., Brumfield, A., Mianulli, M., Poole, L., & Mcintyre, C. W. (2018). Percutaneous perfusion monitoring for the detection of hemodialysis induced cardiovascular injury. Hemodialysis international. International Symposium on Home Hemodialysis, 22(3), 351–358. https://doi.org/10.1111/hdi.12632

2017

Shardlow, A., McIntyre, N. J., Fraser, S., Roderick, P., Raftery, J., Fluck, R. J., McIntyre, C. W., & Taal, M. W. (2017). The clinical utility and cost impact of cystatin C measurement in the diagnosis and management of chronic kidney disease: A primary care cohort study. PLoS medicine, 14(10), e1002400. https://doi.org/10.1371/journal.pmed.1002400

Nerbass, F. B., Pecoits-Filho, R., Clark, W. F., Sontrop, J. M., McIntyre, C. W., & Moist, L. (2017). Occupational Heat Stress and Kidney Health: From Farms to Factories. Kidney international reports, 2(6), 998–1008. https://doi.org/10.1016/j.ekir.2017.08.012

Shardlow, A., McIntyre, N. J., Fluck, R. J., McIntyre, C. W., & Taal, M. W. (2017). Associations of fibroblast growth factor 23, vitamin D and parathyroid hormone with 5-year outcomes in a prospective primary care cohort of people with chronic kidney disease stage 3. BMJ open, 7(8), e016528. https://doi.org/10.1136/bmjopen-2017-016528

Presseau, J., Mutsaers, B., Al-Jaishi, A. A., Squires, J., McIntyre, C. W., Garg, A. X., Sood, M. M., Grimshaw, J. M., & Major outcomes with personalized dialysate TEMPerature (MyTEMP) investigators (2017). Barriers and facilitators to healthcare professional behaviour change in clinical trials using the Theoretical Domains Framework: a case study of a trial of individualized temperature-reduced haemodialysis. Trials, 18(1), 227. https://doi.org/10.1186/s13063-017-1965-9

Mahmoud, H., Forni, L. G., McIntyre, C. W., & Selby, N. M. (2017). Myocardial stunning occurs during intermittent haemodialysis for acute kidney injury. Intensive care medicine, 43(6), 942–944. https://doi.org/10.1007/s00134-017-4768-2

Grant, C. J., Harrison, L. E., Hoad, C. L., Marciani, L., Gowland, P. A., & McIntyre, C. W. (2017). Patients with chronic kidney disease have abnormal upper gastro-intestinal tract digestive function: A study of uremic enteropathy. Journal of gastroenterology and hepatology, 32(2), 372–377. https://doi.org/10.1111/jgh.13458

Li, P. K., Ng, J. K., & Mcintyre, C. W. (2017). Inflammation and Peritoneal Dialysis. Seminars in nephrology, 37(1), 54–65. https://doi.org/10.1016/j.semnephrol.2016.10.007

Hemmett, J., & McIntyre, C. W. (2017). A Dialysis Patient's Choice and a Nephrologist's Obligation: The Need to Understand and Value the Patient's Perspective. Seminars in dialysis, 30(1), 3–5. https://doi.org/10.1111/sdi.12562

Salerno, F. R., Parraga, G., & McIntyre, C. W. (2017). Why Is Your Patient Still Short of Breath? Understanding the Complex Pathophysiology of Dyspnea in Chronic Kidney Disease. Seminars in dialysis, 30(1), 50–57. https://doi.org/10.1111/sdi.12548

Jefferies, H. J., Tertti, R., Wittfooth, S., Burton, J. O., Metsärinne, K., Pettersson, K., & McIntyre, C. W. (2017). Potentially pathogenic circulating autoantibodies to cardiac troponin are present in hemodialysis patients. Hemodialysis international. International Symposium on Home Hemodialysis, 21(4), 519–523. https://doi.org/10.1111/hdi.12514

Buchanan, C., Mohammed, A., Cox, E., Köhler, K., Canaud, B., Taal, M. W., Selby, N. M., Francis, S., & McIntyre, C. W. (2017). Intradialytic Cardiac Magnetic Resonance Imaging to Assess Cardiovascular Responses in a Short-Term Trial of Hemodiafiltration and Hemodialysis. Journal of the American Society of Nephrology: JASN, 28(4), 1269–1277. https://doi.org/10.1681/ASN.2016060686

Salerno, F. R., Parraga, G., & McIntyre, C. W. (2017). Why Is Your Patient Still Short of Breath? Understanding the Complex Pathophysiology of Dyspnea in Chronic Kidney Disease. Seminars in dialysis, 30(1), 50–57. https://doi.org/10.1111/sdi.12548

Pittman, Z. C., John, S. G., & McIntyre, C. W. (2017). Collection of daily patient reported outcomes is feasible and demonstrates differential patient experience in chronic kidney disease. Hemodialysis international. International Symposium on Home Hemodialysis, 21(2), 265–273. https://doi.org/10.1111/hdi.12470 

2016

Shardlow, A., McIntyre, N. J., Fluck, R. J., McIntyre, C. W., & Taal, M. W. (2016). Chronic Kidney Disease in Primary Care: Outcomes after Five Years in a Prospective Cohort Study. PLoS medicine, 13(9), e1002128. https://doi.org/10.1371/journal.pmed.1002128