The following journal articles/abstracts may be used only for your research purposes. They may not be reproduced in any manner without written permission of their respective copyright owner, which is not always me.

Sanjay R. Kharche. Ph.D.

PARTIAL LIST OF PUBLICATIONS

I have over 100 publications, including 43 peer reviewed journal papers. Scopus H-Index: 14; 720 citations. Google Scholar citations: 800, h-index: 17.

    Primary Journal Publications

  1. Yufeng Wang, Zhaohan Xiong, Aaqel Nalar, Brian J. Hansen, Sanjay R. Kharche, Gunnar Seemann, Axel Loewe, Vadim V. Fedorov and Jichao Zhao. A robust computational framework for estimating 3D Bi-Atrial chamber wall thickness. Computers in Biology and Medicine, 2019. vol. 114, article: 103444.
  2. Luiz Altamarino Diaz, Andrea Kassay, Baran Serajelahi, C. W. McIntyre, Guido Filler, and Sanjay R. Kharche. Arterial hypertension and unusual ascending aortic dilatation in a neonate with acute kidney injury: mechanistic computer modelling. Frontiers in Physiology (Computational Medicine). vol 10. 2019. pages 1391. (senior author).
  3. Sunil Jit R. J. Logantha, Sanjay R. Kharche, Yu Zhang, Andrew J. Atkinson, Guoliang Hao , Mark R. Boyett. and Halina Dobrzynski. Sinus node-like pacemaker mechanisms regulate ectopic pacemaker activity in the adult rat atrioventricular ring. Scientific Reports 9. Article number: 11781 (2019).
  4. Ursula Doris, Sanjay R. Kharche, Maria Petkova, Balint Borbas, Sunil Jit R.J. Logantha, Olga Fedorenko, Michal Maczewski, Urszula Mackiewicz, Yu Zhang, Anwar Chahal, Alicia D'Souza, Andrew J Atkinson, Halina Dobrzynski, Joseph Yanni. A sexy approach to pacemaking: differences in function and molecular make up of the sinoatrial node. Histology and Histopathology. 2019. vol. 31. issue 11. pp. 1255-1268.
  5. Tom Sheard, Sanjay R. Kharche, Christian Pinali and Holly A. Shiels. 3-d ultrastructural study of sarcoplasmic reticulum forming calcium release units in avian cardiomyocytes. Journal of Experimental Biology. 2019. 222: jeb197640 .
  6. Sanjay R. Kharche, Aaron So, F Salerno, Ting-Yim Lee, Chris Ellis, Daniel Goldman, C W McIntyre. Computational Assessment of Blood Flow Heterogeneity in Peritoneal Dialysis Patients' Cardiac Ventricles. Front Physiol. 2018; 9: 511.
  7. Sanjay R. Kharche, Vigmond E, Efimov IR, Dobrzynski H (2017) Computational assessment of the functional role of sinoatrial node exit pathways in the human heart. PLoS ONE 12(9): e0183727. https://doi.org/10.1371/journal.pone.0183727
  8. Mario Antonioletti, Vadim N. Biktashev, Adrian Jackson, Sanjay R. Kharche, Tomas Stary, Irina Biktasheva. BeatBox — HPC Simulation Environment for Biophysically and Anatomically Realistic Cardiac Electrophysiology. PLoS ONE 12(5): e0172292. https://doi.org/10.1371/journal.pone.0172292
  9. Zhao J, Sanjay R. Kharche, Hansen BJ, Csepe TA, Wang Y, Stiles MK, Fedorov VV. Optimization of catheter ablation of atrial fibrillation: insights gained from clinically-derived computer models. Int J Mol Sci. 2015;16(5):10834-54. (IF 2.8).
  10. Logantha SJ, Stokke MK, Atkinson AJ, Sanjay R. Kharche, Parveen S, Saeed Y, Sjaastad I, Sejersted OM, Dobrzynski H. Ca(2+)-Clock-Dependent Pacemaking in the Sinus Node Is Impaired in Mice with a Cardiac Specific Reduction in SERCA2 Abundance. Front Physiol. 2016. 7: 197 (IF 5).
  11. Sanjay R. Kharche, Irina V. Biktasheva, Gunnar Seemann, Henggui Zhang, Vadim N. Biktashev. A Computer Simulation Study of Anatomy Induced Drift of Spiral Waves in the Human Atrium BioMed Research International (2015). 2015: 731386. IF: 2.7.
  12. C Moreno, A Oliveras, Sanjay R. Kharche, M Guizy, A de la Cruz, N Comes, T Starý, I Baró, G Loussouarn, S Severi, A Felipe, C Valenzuela. Effects of n-3 polyunsaturated fatty acids on the function, expression and location of Kv7.1 channels. Cardiovasc Res. (2015). 105(2): 223-232.IF:5.9.
  13. Hancox JC, Sanjay R. Kharche, El Harchi A, Stott J, Law P, Zhang H. In silico investigation of a KCNQ1 mutation associated with familial atrial fibrillation. J Electrocardiol. (2014). 47(2): 158-65.
  14. Sanjay R. Kharche, Stary T, Colman MA, Biktasheva IV, Workman AJ, Rankin AC, Holden AV, Zhang H. Effects of human atrial ionic remodelling by β-blocker therapy on mechanisms of atrial fibrillation: a computer simulation. Europace (2014). 16 (10): 1524-33
  15. MA Colman, OV Aslanidi, Sanjay R. Kharche, et al. Pro-arrhythmogenic Effects of Atrial Fibrillation Induced Electrical Remodelling- Insights from 3D Virtual Human Atria. J Physiol. (2013). 591(17): 4249-72.
  16. Sanjay R. Kharche et al. Pro-arrhythmogenic effects of the S140G KCNQ1 mutation in human atrial fibrillation - insights from modelling. J Physiol. (2012). 590(8): 4501-14.
  17. Aslanidi OV,…, Holden AV, Sanjay R. Kharche, et al. Virtual tissue engineering of the human atrium: modelling pharmacological actions on atrial arrythmogenesis. Eur J Pharm Sci. (2012) 46(4): 209-21.
  18. M Zi, TE Kimura, W Liu, J Jin, J Higham, Sanjay R. Kharche, et al. Mitogen-activated protein kinase kinase 4 deficiency in cardiomyocytes causes connexin 43 reduction and couples hypertrophic signals to ventricular arrythmogenesis. J Biol Chem. (2011) 286 (20): 17821-30.
  19. Sanjay R. Kharche, Yu J, Lei M,Zhang H. A mathematical model of action potentials of mouse sinoatrial node cells with molecular bases. Am J Physiol (2011) 301(3): H945-63.
  20. Tong WC, Choi CY, Sanjay R. Kharche, et al. A computational model of the ionic currents, Ca2+ dynamics and action potentials underlying contraction of isolated uterine smooth muscle. PLoS One. 2011. 6(4):e18685
  21. 15Sanjay R. Kharche, G N;Lüdtke, S Panzeri and H;Zhang. A Global Sensitivity Index for Biophysically Detailed Cardiac Cell Models: A Computational Approach. LNCS (2009); 5528: 366-375.
  22. Sanjay R. Kharche, Garratt CJ, Boyett MR, Inada S, Holden AV, Hancox JC, Zhang H. Atrial proarrhythmia due to increased inward rectifier current (IK1) arising from KCNJ2 mutation – A simulation study. PBMB. 98: (2-3): pp. 186-197; (2008) (I.F.: 5).
  23. H. Wright, R.H. Crompton, Sanjay R. Kharche, P. Wenisch. Steering and visualization: Enabling technologies for computational science. Future Generation Computer Systems (2010); 26(3): 506-513. (I.F.: 1.5).
  24. H Zhang, T Tao, Sanjay R. Kharche, S M Harrison. Modelling changes in transmural propagation and susceptibility to arrhythmia induced by volatile anaesthetics in ventricular tissue. J. Theo. Biol. 257(2): pp. 279-291. (I.F.: 2.3).
  25. Sanjay R. Kharche, G Seemann, L Margetts, J Leng, A V Holden, H Zhang. Simulation of clinical electrophysiology in 3D human atria: a high-performance computing and high-performance visualization application. Conc. Comput.: Practice and Experience. (2008); 20(11): 1317-1328.
  26. Howarth FC, Chandler NJ, Sanjay R. Kharche, et al. Effects of streptozotocin-induced diabetes on connexin43 mRNA and protein expression in ventricular muscle. Mol Cell Biochem. (2008); 319(1-2): 105-114. (I.F.: 1.9).
  27. H Zhang, Sanjay R. Kharche, A V Holden, J C Hancox. Repolarisation and vulnerability to re-entry in the human heart with short QT syndrome arising from KCNQ1 mutation--A simulation study. PBMB. 96 (1-3): 2008. (I.F.: 5.009).
  28. H Zhang, C J Garratt, Sanjay R. Kharche, A V Holden. Remodelling of cellular excitation (reaction) and intercellular coupling (diffusion) by chronic atrial fibrillation represented by a reaction-diffusion system, Physica D: Nonlinear Phenomena. 238: 976-983; 2009. (I.F.: 1.735).
  29. Salle; L, Sanjay R. Kharche, Zhang H, Brette F. Mechanisms underlying adaptation of action potential duration by pacing rate in rat myocytes. PBMB 96 (1-3): 305-20. 2008. (joint first author) (I.F.: 5.009).
  30. Taggart MJ, Blanks A, Sanjay R. Kharche, et al. Towards understanding the myometrial physiome: approaches for the construction of a virtual physiological uterus. BMC Pregnancy Childbirth. (2007). 7 (Sup: 1:S3).
  31. Sanjay R. Kharche, G Seemann, J Leng, AV Holden, CJ Garratt, H Zhang. Waves in 3D Virtual Human Atria: A Computational Study. F.B. Sachse and G. Seemann (Eds.): LNCS (2007); 4466: 129–138.
  32. AP Benson, RH Clayton, AV Holden, Sanjay R. Kharche, WC Tong. Endogenous driving and synchronization in cardiac and uterine tissues: bifurcations and local coupling. Philos. Tans. Roy. Soc. 364 (1842): 1313-1327; (2006).
  33. Sanjay R. Kharche, H Zhang, AV Holden. Hypertrophy in rat virtual left ventricular cells and tissue. A. F. Frangi et al. (Eds): LNCS (2005); 3504: 153-161.
  34. Sanjay R. Kharche, JA Howarth. The inward solidification of a liquid cylinder with periodic axial perturbation of the boundary temperature or heat flux. Int. Comms. Heat and Mass. (2000); 27 (7): 903-912.
  35. Sanjay R. Kharche, JA Howarth. The inward solidification of a liquid cylinder with periodic axial perturbation of the boundary geometry, and constant temperature or heat flux. Int. Comms. Heat and Mass. (2000); 27 (7): 913-923.
  36. Book Chapter

  37. Sanjay R. Kharche, Phillip R. Law and Henggui Zhang (2009). Studying Ion Channel Dysfunction and Arrythmogenesis in the Human Atrium: A Computational Approach, Recent Advances in Biomedical Engineering, Ganesh R Naik (Ed.), ISBN: 978-953-307-004-9, InTech, DOI: 10.5772/7468.
  38. Work in progress

  39. Sanjay R. Kharche and CW McIntyre. Computationally assessing the effectiveness of therapeutic hypothermia on human cardiac ventricular function in light of electrophysiological ischemia and structural fibrosis (in preparation for Scientific Reports).
  40. Sanjay R. Kharche, Andrew Atkinson, Halina Dobrzynski, C. W. McIntyre. Computationally assessing the role of sinoatrial node exit pathways in a biophysically detailed electrically active human 3D model (in preparation for Scientific Reports).
  41. Sanjay R. Kharche, J. J. Joseph, C. W. McIntyre, et al. Construction and validation of a high resolution ECG monitor - a cost effective design.
  42. Sanjay R. Kharche, J. J. Joseph, Geoff Wild, C. W. McIntyre. Uncertainty quantification in human cardiomyocyte mathematical models for reliability of a whole organ simulator: use of novel sensitivity analysis methods.
  43. Sanjay R. Kharche, Kairavi Desai, Foram Patel, C. W. McIntyre, et al. A cardiomyocyte to 3D electrically-spatially heterogeneous computational model of the whole mouse heart capable of producing ECG. (In preparation for American Journal Physiology Heart and Circulation).
  44. Sunil Logantha, Sanjay R. Kharche, Halina Dobrzynski et al. Gap junction function at the coupling of mouse SAN atrial cells.
  45. Selected conference publications

  46. Q. Wang, Sanjay R. Kharche, G. Jones, C. Luo, C. Tang and H. Zhang, "Calcium leak induced sinus bradycardia," 2015 Computing in Cardiology Conference (CinC), Nice, 2015, pp. 1109-1112.
  47. Sanjay R. Kharche. A nice new conference paper.
  48. A. J. Atkinson, Sanjay R. Kharche, M. G. Bateman, P. A. Iaizzo and H. Dobrzynski, "3D anatomical reconstruction of human cardiac conduction system and simulation of bundle branch block after TAVI procedure," 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Orlando, FL, 2016, pp. 5583-5586.
  49. M A Colman, Sanjay R. Kharche, H Zhang. Loss of Transverse T-tubules Promotes the Development of Ectopic Activity in Guinea-pig Ventricle. Computing in Cardiology (2014).
  50. Sanjay R. Kharche, J Zhao, S Castro, M Colman, R Stevenson, J Jarvis, B Smail, H Zhang. Role of fiber orientation in atrial arrythmogenesis. Computing in Cardiology (2014).
  51. Sanjay R. Kharche, E J Vigmond, M Colman, H Zhang. Ischemia alters sensitivity of action potential to the sodium-potassium pump. Computing in Cardiology (2014).
  52. SJ Castro, MA Colman, Sanjay R. Kharche, Ruoxi Wang, Henggui Zhang. HCN and SCN5A Channel Mutations: Implications for Impaired Atrioventricular Nodal Conduction in a Heterogeneous Computer Model of the Whole Mouse Heart. Computing in Cardiology (2013).
  53. Sanjay R. Kharche, Biktasheva IV, Zhang H, Biktashev VN. Simulating the role of anisotropy in human atrial cardioversion. Conf Proc IEEE Eng Med Biol Soc. (2013). 2013: 6838-41.
  54. Sanjay R. Kharche, Beling J, Biktasheva IV, Zhang H, Biktashev VN. Simulating cell apoptosis induced sinus node dysfunction. Conf Proc IEEE Eng Med Biol Soc. (2013). 2013: 6842-5.
  55. Sanjay R. Kharche, A Jackson, IV Biktasheva, VN Biktashev. Simulation of Low Energy Defibrillation Using a Novel Cardiac Simulation Environment, Beatbox. Digital Research 2012 Conference, Oxford.
  56. Sanjay R. Kharche.Low Energy Cardioversion Using Feedback Stimuli in Human Atria. Multiscale Modelling in Medicine and Biology: 3-5 Sept. 2012. Centre for Mathematical Medicine and Biology, University of Nottingham.
  57. Sanjay R. Kharche, Giulia Callisesi, T Stary, A Bracci, S Severi. Simulating the Effects of Serum Potassium on the ECG. Computing in Cardiology 2012; 39:225-228.
  58. Sanjay R. Kharche, IV Biktasheva, G Seemann, H Zhang, VN Biktashev. Cardioversion Using Feedback Stimuli in Human Atria. Computing in Cardiology 2012; 39:133-136.
  59. Y Yuan, K Wang, Sanjay R. Kharche, H Zhang. Vulnerability to Re-entry Arising from LPC-Induced Alterations of Cardiac Sodium Current Kinetics: A Simulation Study. Computing in Cardiology 2011; 38:653-656.
  60. Corsi C, Sanjay R. Kharche, DeBie J, Bloise R, Napolitano C, Priori SG, Santoro A, Mortara D, Severi S. ECG based blood potassium estimates. Fundam Clin Pharmacol 2011;25:IV.
  61. P Law, Sanjay R. Kharche, J Higham, H Zhang. Anti-arrhythmic Effects of Atrial Specific IKur Block: A Simulation Study. Computing in Cardiology 2010;37:429-432.
  62. Sanjay R. Kharche, J Higham, M Lei, H Zhang. Functional Roles of Ionic Currents in a Membrane Delimited Mouse Sino-atrial Node Model. Computing in Cardiology 2010; 37:421−424.
  63. Sanjay R. Kharche et al. Global Sensitivity Indexing in Biophysically Detailed Cardiac Cell Models: A High Performance Computing Application. Talk at the UK E-science All Hands Meeting. December 2009.
  64. Law P, Sanjay R. Kharche, et al. Effects of elevated Homocysteine hormone on electrical activity in the human atrium: A simulation study. Conf Proc IEEE Eng Med Biol Soc. 2009;1:3936-9.
  65. Sanjay R. Kharche, Jian Yu, Ming Lei, Henggui Zhang. Contribution of Kinetically Distinct HCN Isoforms to Murine Pacemaking: A Computational Study. General Meeting of The Physiological Society, Dublin (2009).
  66. J Stott, Sanjay R. Kharche, P Law, H Zhang. Simulating the Effects of Atrial Fibrillation in Electrically Heterogeneous Human Atria: A Computer Modelling Study. Computers in Cardiology 2008.
  67. Sanjay R. Kharche; Zhang, H, "Simulating the effects of atrial fibrillation induced electrical remodeling: A comprehensive simulation study," Conf Proc IEEE Eng Med Biol Soc.2008; 2008:593-6
  68. K. Wang, Y. Yuan, Sanjay R. Kharche and H. Zhang, "The E1784K mutation in SCN5A and phenotypic overlap of Type 3 Long QT syndrome and Brugada syndrome: A simulation study," 2009 36th Annual Computers in Cardiology Conference (CinC), Park City, UT, 2009, pp. 301-304.
  69. Sanjay R. Kharche, CJ Garratt, AV Holden, H Zhang. (2007). Stability of Scroll Excitation Waves in Human Atria during Fibrillation: A Computational Study. Computers in Cardiology. 34:285−288.
  70. H. Zhang, Sanjay R. Kharche, P. Stewart and J. C. Hancox, "Mechanistic insights to pro-arrhythmogenesis of short-QT syndrome associated with KCNQ1 gene mutation," 2007 Computers in Cardiology, Durham, NC, 2007, pp. 245-248.
  71. IJ Grimstead, Sanjay R. Kharche, H Zhang, NJ Avis, DW Walker. Viewing 0.3Tb Heart Simulation Data At Your Desk. EG UK Theory and Practice of Computer Graphics (2007), pp. 1-7. Ik Soo Lim, David Duce (Eds).
  72. Sanjay R. Kharche, G Seemann, L Margetts, AV Holden, H Zhang. eScience simulation of clinical electrophysiology in 3D human atrium. UK e-science All Hands Meeting, 2006. Nottingham.
  73. 30. Sanjay R. Kharche, AV Holden, H Zhang. Vulnerability in one-dimensional transmural model of human ventricular tissue in heart failure. Computers in Cardiology. (2005); 32: 563-566.
  74. 29. Sanjay R. Kharche, H Zhang, RH Clayton, AV Holden. Simulation of Hypertrophy in rat left ventricular cells. Computers in Cardiology. (2004); 31: 513-516.
  75. Sanjay R. Kharche, H Moore, CJ Garatt, JC Hancox, H Zhang. Gain-of-function in Kir2.1 and its effects on atrial fibrillation in homogenous virtual human atrial tissue: a computer simulation study. International Society of Computerized Electrophysiology, Niagara-on-the-Lake, April 2006.
  76. AP Benson, AV Holden, Sanjay R. Kharche, WC Tong. From gene expression to tissue dynamics via continuation algorithms: pacemaking in the heart. In Plotkin G (Ed). Proceedings of the International Workshop on Computational Methods in Systems Biology, Edinburgh. 3-5 April 2005.pp 192-203.
  77. Sanjay R. Kharche, Kairavi Desai, Christopher W. McIntyre. Elucidating the relationship between arrhythmia and ischemic heterogeneity: an in silico study. Engineering in Medicine and Biology Society. 2020 Accepted.
  78. Jermiah J. Joseph, Christopher W. McIntyre, Sanjay R. Kharche. Proarrhythmic Effects of Electrolyte Imbalance in Virtual Human Atrial and Ventricular Cardiomyocytes. Engineering in Medicine and Biology Society. 2020 Accepted.
  79. Sanjay R. Kharche,Chen Yanru, and Christopher W. McIntyre. Fractal Dimension Based Texture Analysis of CT Perfusion Imaging. Engineering in Medicine and Biology Society. 2020 Accepted.
  80. Chen Yanru, Sanjay R. Kharche,Yan Min Zhang, GH Janssen, and Christopher W. McIntyre. Quantifying microvascular alterations due to a pharmacological agent. Engineering in Medicine and Biology Society. 2020 Accepted.
  81. B. Serajelahi, Sanjay R. Kharche, D. Goldman. Steady-State Tissue Oxygen Distributions Calculated by a Green\92s Function Method and a Finite Difference Method: A Comparison. Engineering in Medicine and Biology Society. 2020 Accepted.
  82. Sanjay R. Kharche, Foram Patel, Kairavi Desai, Christopher W. McIntyre. Simulating Small Animal Atrial Cardiomyocyte Action Potentials: A Preliminary study. Engineering in Medicine and Biology Society. 2020 Accepted.
  83. Selected abstracts publications

  84. Sanjay R. Kharche. Is Insulating Border Necessary for Human Sinoatrial Node Spontaneous Activity? (talk in CompBioMed conference, 2019, London).
  85. Sanjay R. Kharche. In Silico Assessment of Cardio-protection by Therapeutic Hypothermia. (talk in CompBioMed conference, 2019, London).
  86. Sanjay R. Kharche, Wenyao Xia, Andrea D. Kassay, Jermiah Joseph, Kierra D. McDougall, Terry M. Peters, Christopher W. McIntyre. Bioengineering Quantification of the Effects of a Haemodialysis Patient's Cardiac Ejection Fraction: Towards Patient Specific Risk Prediction. American Society of Nephrology Annual Conference. San Diego. 2018.
  87. Sanjay R. Kharche,Raanan Marants,Elena Qirjazi, Andrea D. Kassay, Jermiah Joseph, Kierra D. McDougall, Ting Lee, Christopher W. McIntyre. Understanding the Effects of Haemodialysis on Blood Flow: An Imaging-Mathematical Modeling Study. American Society of Nephrology Annual Conference. San Diego. 2018.
  88. Sanjay R. Kharche, C W McIntyre. Computational assessment of arrhythmia potential in the heterogeneously perfused ventricle. Cardiac Physiome Workshop, Toronto. 2017.
  89. Sanjay R. Kharche, C W McIntyre. Computational assessment of arrhythmia potential in the heterogeneously perfused ventricle. European Heart Rhythm Association meeting, Vienna, 2017.
  90. Sanjay R. Kharche, M. Boyett1, H. Dobrzynski. Computational modelling of the mouse sino-atrial node: Exit block due to apoptosis. Physiology 2015 (Cardiff, UK) (2015) Proc Physiol Soc 34, PC007.
  91. Sanjay R. Kharche, H. Dobrzynski. Complexity of the human sinoatrial node: A computational investigation. Physiology 2016 (Dublin, Ireland) (2016) Proc Physiol Soc 37, PCA012.
  92. E. Perez Alday, M. Coman, P. Langley, D. Giacopelli, Sanjay R. Kharche, H. Zhang. New algorithm to diagnose atrial ectopic origin from 64 lead ECG - insights from 3D virtual human atria and torso. Proc Physiol Soc 31 (2014) PCA044
  93. 74. Sanjay R. Kharche, J. Zhao, S. Castro, R. Stevenson, J. Jarvis, B. Smail, H. Zhang. (2014). Activation regulation by fiber orientation in the rabbit atria. Proc Physiol Soc 31, PCA010
  94. M A Colman, O V Aslanidi, Sanjay R. Kharche, M R Boyett, H Zhang. The effect of AF-induced electrical remodelling on regional electrical heterogeneity and tissue vulnerability to atrial fibrillation – insights from modelling. (2013). J Electrocardiology 46(4): e18.
  95. 72. Sanjay R. Kharche et al. Effects of human atrial ionic remodelling by β-blocker therapy on mechanisms of atrial fibrillation: a computer simulation. Journal of Electrocardiology, 46(4): e6.
  96. Sanjay R. Kharche et al. Computer Simulation of the Role of Fibre Orientation in Cardioversion of Chronic Atrial Fibrillation. (2013). J Electrocardiology 46(4): e6-e7.
  97. Sanjay R. Kharche et al. Effects of human atrial ionic remodelling by β-blocker therapy on mechanisms of AF: a computer simulation. (2013). J Electrocardiology 46(4): e6.
  98. Sanjay R. Kharche et al. (2013). Simulating Cell Apoptosis Induced Sinus Node Dysfunction. Proc 37th IUPS, PCA018
  99. Sanjay R. Kharche, T Stary, IV Biktasheva, H Zhang, VN Biktashev. (2013) The Role of Fibre Orientation in Cardioversion of Chronic Atrial Fibrillation: A Simulation Study. Proc 37th IUPS, PCA017
  100. Sanjay R. Kharche, T. Stary, G. Callisesi, A. Bracci, S. Severi (2012)Correlating serum potassium levels to ECG: A simulation study. Proc Physiol Soc 27, PC27.
  101. Sanjay R. Kharche, I. V. Biktasheva, V. N. Biktashev (2012) Beatbox: A novel multi-function cardiac simulation environment. Proc Physiol Soc 27, PC26
  102. Sanjay R. Kharche, T. Burchell, C. E. Astles, H. Zhang (2011) Computer Simulation of Human Atrial Fibrillation due to S140G and V141M Mutations of the Kv7.1 Gene. Proc Physiol Soc 23, PC251
  103. G. Callisesi, Sanjay R. Kharche, S. Severi. (2011)M Cells in Humans: Action Potential Modelling and Impact on APD Distribution in Cardiac Tissue. Proc Physiol Soc 23, PC140
  104. P. Law, Sanjay R. Kharche, H. Zhang. (2010) Anti-arrythmogenic Effects of Atrial Specific IKur Block: A Modelling Study. Proc Physiol Soc 19, PC14
  105. Sanjay R. Kharche, M. Lei, H. Zhang (2010) Functional Roles of Ionic Currents in A Membrane Delimited Mouse Sino-atrial Node Cell Model. Proc Physiol Soc 19, C99
  106. Sanjay R. Kharche, L. Ming, H. Zhang (2009). A Systems Biology Computational Comparison of Two Cardiac Pacemaker Cell ModelsProc Physiol Soc 15, PC115.
  107. P. R. Law, J. Stott, Sanjay R. Kharche, H. Zhang (2009). Conduction Propagation Dysfunction with No Apparent Changes in Cellular Electrical Action Potentials in Human Atria: A Simulation Study.Proc Physiol Soc 15, PC11
  108. Sanjay R. Kharche, J. Yu, M. Lei, H. Zhang (2009)Contribution of Kinetically Distinct HCN Isoforms to Murine Pacemaking: A Computational Study Proc Physiol Soc 15, C16
  109. Sanjay R. Kharche, J. Stott, P. Law, H. Dobrzynski, H. Zhang;(2008). Effects of atrial fibrillation on electrically heterogeneous human atria: a computer modelling study Proc Physiol Soc 11C20
  110. Sanjay R. Kharche, Henggui Zhang, Laurent Sallé, Fabien Brette. (2007). Computational investigation of the adaptation of action potential duration by pacing rate in rat myocytes. J. Mol. Cell. Cardiol 42(6): pp S1-S2.
  111. Sanjay R. Kharche, J. Stott, P. Law, H. Zhang, J. C. Hancox;(2007). Computational evaluation of the effects of novel anionic currents on human atrial electrical behaviourProc Physiol Soc 8PC8
  112. T. Tao, S. C. O'Neill, Sanjay R. Kharche, H. Zhang;(2007)Mechanism of Ca intracellular alternans produced by low depolarization - A study by a stochastic [Ca2+]i handling model. Proc. Physiol. Soc. 8PC33
  113. Sanjay R. Kharche, J. Stott, M. R. Boyett, H. Zhang;(2007)Pro-arrhythmogenic effects of Kir2.1 and KvLQT1 familial gene mutations in human atrium: a computational study. Proc. Life SciencesPC146
  114. Sanjay R. Kharche et al. (2006)Gain-of-function in Kir2.1 and its effects on atrial fibrillation in homogeneous virtual human atrial tissue: a computer simulation study Proc. Physiol. Soc. 3PC39
  115. Sanjay R. Kharche et al. (2006). Gain of function in Kir2.1 and its effects on atrial fibrillation in homogeneous virtual human atrial tissue: a computer simulation study, Journal of Electrocardiology, Volume 39(4): Suppl. 1, pp. S83
  116. Sanjay R. Kharche, H Zhang, AV Holden (2005)Action potential duration, conduction velocity restitution, and vulnerability to re-entry in a computational model of human failing heart tissue J Physiol 567P PC12
  117. Sanjay R. Kharche et al. (2004)Synchronization and Bursting in a Simple Gravid Uterus.J Physiol 561P PC16
  118. Ph.D. Thesis

  119. Sanjay R. Kharche. Stefan Problems with Two Dimensional Linearised Perturbations in Their Boundary Geometry or Boundary Conditions. Ph.D. thesis at the University of Hull, Hull, UK (September 2000).



  120. Home Research Publications Funding Data and models Contact Outreach Resources Teaching and for Students



    August 5th, 2020. Dr. Sanjay R. Kharche.